Chaperone‐mediated autophagy: Molecular mechanisms, biological functions, and diseases

Abstract Chaperone‐mediated autophagy (CMA) is a lysosomal degradation pathway that eliminates substrate proteins through heat‐shock cognate protein 70 recognition and lysosome‐associated membrane protein type 2A‐assisted translocation. It is distinct from macroautophagy and microautophagy. In recen...

Full description

Bibliographic Details
Main Authors: Ruchen Yao, Jun Shen
Format: Article
Language:English
Published: Wiley 2023-10-01
Series:MedComm
Subjects:
Online Access:https://doi.org/10.1002/mco2.347