Fasudil and viscosity of gelatin promote hepatic differentiation by regulating organelles in human umbilical cord matrix-mesenchymal stem cells

Fasudil and viscosity of gelatin promote hepatic differentiation by regulating organelles in human umbilical cord matrix-mesenchymal stem cells

Abstract Background Human mesenchymal stem cells originating from umbilical cord matrix are a promising therapeutic resource, and their differentiated cells are spotlighted as a tissue regeneration treatment. However, there are limitations to the medical use of differentiated cells from human umbili...

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Bibliographic Details
Main Authors: Jiwan Choi, Seoon Kang, Hye-In An, Chae-Eun Kim, Sanghwa Lee, Chan-Gi Pack, Young-In Yoon, Hana Jin, Yong-Pil Cho, Chong Jai Kim, Jung-Man Namgoong, Jun Ki Kim, Eunyoung Tak
Format: Article
Language:English
Published: BMC 2024-07-01
Series:Stem Cell Research & Therapy
Subjects:
Human umbilical cord matrix-mesenchymal stem cells
Gelatin viscosity
ROCK inhibitor
Fasudil
Hepatic differentiation
Mitochondria activation
Online Access:https://doi.org/10.1186/s13287-024-03851-9

Internet

https://doi.org/10.1186/s13287-024-03851-9

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