Nicotine but not saline self-administering or yoked control conditions produces sustained neuroadaptations in the accumbens shell

IntroductionUsing yoked animals as the control when monitoring operant drug-self-administration is considered the golden standard. However, instrumental learning per se recruits several neurocircuits that may produce distinct or overlapping neuroadaptations with drugs of abuse. The aim of this proje...

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Bibliographic Details
Main Authors: Ana Domi, Erika Lucente, Davide Cadeddu, Louise Adermark
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2023.1105388/full