HIV-Quasipore: A Suite of HIV-1-Specific Nanopore Basecallers Designed to Enhance Viral Quasispecies Detection

HIV-Quasipore: A Suite of HIV-1-Specific Nanopore Basecallers Designed to Enhance Viral Quasispecies Detection

Accounting for genetic variation is an essential consideration during human immunodeficiency virus type 1 (HIV-1) investigation. Nanopore sequencing preserves proviral integrity by passing long genomic fragments through ionic channels, allowing reads that span the entire genome of different viral qu...

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Bibliographic Details
Main Authors: Robert W. Link, Diehl R. De Souza, Cassandra Spector, Anthony R. Mele, Cheng-Han Chung, Michael R. Nonnemacher, Brian Wigdahl, Will Dampier
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Virology
Subjects:
HIV-1
nanopore
viral quasispecies
sequencing
deep learning
genetic diversity
Online Access:https://www.frontiersin.org/articles/10.3389/fviro.2022.858375/full

Internet

https://www.frontiersin.org/articles/10.3389/fviro.2022.858375/full

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