Effect of RUNX1/FOXP3 axis on apoptosis of T and B lymphocytes and immunosuppression in sepsis

Lymphocyte apoptosis is a latent factor for immunosuppression in sepsis. Forkhead box protein P3 (FOXP3) can interact with RUNX family transcription factor 1 (RUNX1) in regulatory T cells. Our research was to probe whether RUNX1/FOXP3 axis affects immunosuppression in the process of sepsis by modula...

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Bibliographic Details
Main Authors: Chao Yangfa, Huang Wenting, Xu Zhiheng, Li Ping, Gu Shaodong
Format: Article
Language:English
Published: De Gruyter 2023-08-01
Series:Open Medicine
Subjects:
Online Access:https://doi.org/10.1515/med-2023-0728