Crystal structure of Zika virus NS5 RNA-dependent RNA polymerase

Crystal structure of Zika virus NS5 RNA-dependent RNA polymerase

The Zika virus outbreak is a global health threat and there is an urgent need for drugs against the virus. Here the authors present the structure of the RNA-dependent RNA-polymerase domain from Zika non-structural protein 5, which is a template for the design of non-nucleoside polymerase inhibitors.

Bibliografiska uppgifter
Huvudupphovsmän: Andre S. Godoy, Gustavo M. A. Lima, Ketllyn I. Z. Oliveira, Naiara U. Torres, Fernando V. Maluf, Rafael V. C. Guido, Glaucius Oliva
Materialtyp: Artikel
Språk:English
Publicerad: Nature Portfolio 2017-03-01
Serie:Nature Communications
Länkar:https://doi.org/10.1038/ncomms14764

Internet

https://doi.org/10.1038/ncomms14764

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