A Splice Defect in the EDA Gene in Dogs with an X-Linked Hypohidrotic Ectodermal Dysplasia (XLHED) Phenotype

A Splice Defect in the EDA Gene in Dogs with an X-Linked Hypohidrotic Ectodermal Dysplasia (XLHED) Phenotype

X-linked hypohidrotic ectodermal dysplasia (XLHED) caused by variants in the EDA gene represents the most common ectodermal dysplasia in humans. We investigated three male mixed-breed dogs with an ectodermal dysplasia phenotype characterized by marked hypotrichosis and multifocal complete alopecia,...

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Bibliographic Details
Main Authors: Dominik P. Waluk, Gila Zur, Ronnie Kaufmann, Monika M. Welle, Vidhya Jagannathan, Cord Drögemüller, Eliane J. Müller, Tosso Leeb, Arnaud Galichet
Format: Article
Language:English
Published: Oxford University Press 2016-09-01
Series:G3: Genes, Genomes, Genetics
Subjects:
Canis familiaris
RNA-seq
splicing
X-chromosome
skin
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.116.033225

Internet

http://g3journal.org/lookup/doi/10.1534/g3.116.033225

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