Antitumor Activity of an Anti-EGFR/HER2 Bispecific Antibody in a Mouse Xenograft Model of Canine Osteosarcoma

Antitumor Activity of an Anti-EGFR/HER2 Bispecific Antibody in a Mouse Xenograft Model of Canine Osteosarcoma

The overexpression of epidermal growth factor receptors (EGFRs) has been reported in various human tumors, including breast, gastric, lung, colorectal, and pancreatic cancers. Humanized anti-EGFR and anti-human epidermal growth factor receptor 2 (HER2) monoclonal antibodies (mAbs) have been shown to...

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Detaylı Bibliyografya
Asıl Yazarlar: Nami Tateyama, Hiroyuki Suzuki, Tomokazu Ohishi, Teizo Asano, Tomohiro Tanaka, Takuya Mizuno, Takeo Yoshikawa, Manabu Kawada, Mika K. Kaneko, Yukinari Kato
Materyal Türü: Makale
Dil:English
Baskı/Yayın Bilgisi: MDPI AG 2022-11-01
Seri Bilgileri:Pharmaceutics
Konular:
EGFR
HER2
bispecific antibody
ADCC
CDC
canine osteosarcoma
Online Erişim:https://www.mdpi.com/1999-4923/14/11/2494

Internet

https://www.mdpi.com/1999-4923/14/11/2494

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