Glycine-induced NMDA receptor internalization provides neuroprotection and preserves vasculature following ischemic stroke

Glycine-induced NMDA receptor internalization provides neuroprotection and preserves vasculature following ischemic stroke

Summary: Ischemic stroke is the second leading cause of death worldwide. Following an ischemic event, neuronal death is triggered by uncontrolled glutamate release leading to overactivation of glutamate sensitive N-methyl-d-aspartate receptor (NMDAR). For gating, NMDARs require not only the binding...

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Bibliographic Details
Main Authors: Julia Cappelli, Pamela Khacho, Boyang Wang, Alexandra Sokolovski, Wafae Bakkar, Sophie Raymond, Nina Ahlskog, Julian Pitney, Junzheng Wu, Prakash Chudalayandi, Adrian Y.C. Wong, Richard Bergeron
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:iScience
Subjects:
Neuroscience
Molecular neuroscience
Cellular neuroscience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221015108

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http://www.sciencedirect.com/science/article/pii/S2589004221015108

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