Carveol mitigates the development of the morphine anti-nociceptive tolerance, physical dependence, and conditioned place preference in mice

Carveol mitigates the development of the morphine anti-nociceptive tolerance, physical dependence, and conditioned place preference in mice

Emergence of analgesic tolerance and dependence to morphine is frequently the limiting factor in the use of this agent in the management of pain. Hence, this study aimed to investigate the beneficial effects of the natural compound carveol (CV) against morphine antinociceptive tolerance, dependence...

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Bibliographic Details
Main Authors: Ismail Badshah, Neelum Gul Qazi, Maira Anwar, Bushra Shaukat, Muhammad Imran Khan, Babar Murtaza
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Heliyon
Subjects:
Carveol
Morphine
Tolerance
Dependence
NMDA
Nitric oxide
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024038404

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http://www.sciencedirect.com/science/article/pii/S2405844024038404

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