Generation of a human iPSC-derived cardiomyocyte/fibroblast engineered heart tissue model [version 1; peer review: 1 approved, 2 approved with reservations]

Generation of a human iPSC-derived cardiomyocyte/fibroblast engineered heart tissue model [version 1; peer review: 1 approved, 2 approved with reservations]

Animal models have proven integral to broadening our understanding of complex cardiac diseases but have been hampered by significant species-dependent differences in cellular physiology. Human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) have shown great promise in the modelling...

Full description

Bibliographic Details
Main Authors: Chris Denning, Andrew P Holmes, Katja Gehmlich, Nguyen T N Vo, Paulus Kirchhof, Jonas Euchner, Amar J Azad, Max J Cumberland
Format: Article
Language:English
Published: F1000 Research Ltd 2023-09-01
Series:F1000Research
Subjects:
Engineered Heart Tissue (EHT)
3D cardiac model
induced pluripotent stem cell derived cardiomyocytes (iPSC-CM)
induced pluripotent stem cell derived cardiac fibroblasts (iPSC-CF)
cardiac co-culture
cardiac fibrosis
eng
Online Access:https://f1000research.com/articles/12-1224/v1

Internet

https://f1000research.com/articles/12-1224/v1

Similar Items