The Target of Rapamycin Signalling Pathway in Ageing and Lifespan Regulation

Ageing is a complex trait controlled by genes and the environment. The highly conserved mechanistic target of rapamycin signalling pathway (mTOR) is a major regulator of lifespan in all eukaryotes and is thought to be mediating some of the effects of dietary restriction. mTOR is a rheostat of energy...

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Bibliographic Details
Main Authors: Ivana Bjedov, Charalampos Rallis
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/11/9/1043