NO signaling and S-nitrosylation regulate PTEN inhibition in neurodegeneration

NO signaling and S-nitrosylation regulate PTEN inhibition in neurodegeneration

<p>Abstract</p> <p>Background</p> <p>The phosphatase PTEN governs the phosphoinositide 3-kinase (PI3K)/Akt signaling pathway which is arguably the most important pro-survival pathway in neurons. Recently, PTEN has also been implicated in multiple important CNS functions...

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Bibliographic Details
Main Authors: Lipton Stuart A, Hsu Janet, Chen Yaomin, Zhang Xue, Diao Shiyong, Ma Tao, Kwak Young-Don, Masliah Eliezer, Xu Huaxi, Liao Francesca-Fang
Format: Article
Language:English
Published: BMC 2010-11-01
Series:Molecular Neurodegeneration
Online Access:http://www.molecularneurodegeneration.com/content/5/1/49

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http://www.molecularneurodegeneration.com/content/5/1/49

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