Bisphenol A Promotes the Progression of Colon Cancer Through Dual-Targeting of NADPH Oxidase and Mitochondrial Electron-Transport Chain to Produce ROS and Activating HIF-1α/VEGF/PI3K/AKT Axis

Bisphenol A Promotes the Progression of Colon Cancer Through Dual-Targeting of NADPH Oxidase and Mitochondrial Electron-Transport Chain to Produce ROS and Activating HIF-1α/VEGF/PI3K/AKT Axis

Bisphenol A (BPA) is a high-production-volume industrial chemical. Despite recent research conducted on its carcinogenicity, its role in the development of colon cancer (CC) has been rarely studied. This study aims to evaluate the effects of BPA on the migration and invasion of CC cells. First, we c...

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Bibliographic Details
Main Authors: Tianyi Xia, Junnan Guo, Bomiao Zhang, Chengxin Song, Qunye Zhao, Binbin Cui, Yanlong Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Endocrinology
Subjects:
bisphenol A
colon cancer
progression
ROS
HIF-1α/VEGF/PI3K/AKT axis
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.933051/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2022.933051/full

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