Structural basis for divergent C–H hydroxylation selectivity in two Rieske oxygenases

Rieske oxygenases are iron-dependent enzymes that catalyse C–H mono- and dihydroxylation reactions. Here, the authors characterise two cyanobacterial Rieske oxygenases, SxtT and GxtA that are involved in the biosynthesis of paralytic shellfish toxins and determine their substrate free and saxitoxin...

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Bibliographic Details
Main Authors: April L. Lukowski, Jianxin Liu, Jennifer Bridwell-Rabb, Alison R. H. Narayan
Format: Article
Language:English
Published: Nature Portfolio 2020-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-16729-0