Mitochondrial-mediated apoptosis as a therapeutic target for FNC (2′-deoxy-2′-b-fluoro-4′-azidocytidine)-induced inhibition of Dalton’s lymphoma growth and proliferation

Mitochondrial-mediated apoptosis as a therapeutic target for FNC (2′-deoxy-2′-b-fluoro-4′-azidocytidine)-induced inhibition of Dalton’s lymphoma growth and proliferation

Abstract Purpose T-cell lymphomas, refer to a diverse set of lymphomas that originate from T-cells, a type of white blood cell, with limited treatment options. This investigation aimed to assess the efficacy and mechanism of a novel fluorinated nucleoside analogue (FNA), 2′-deoxy-2′-β-fluoro-4′-azid...

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Bibliographic Details
Main Authors: Naveen Kumar, Sanjeev Kumar, Alok Shukla, Sanjay Kumar, Rishi Kant Singh, Ilya Ulasov, Sandeep Kumar, Anand Kumar Patel, Lokesh Yadav, Ruchi Tiwari, Rachana, Shivashish Priyadarshi Mohanta, Kaushalendra, Vikram Delu, Arbind Acharya
Format: Article
Language:English
Published: Springer 2024-01-01
Series:Discover Oncology
Subjects:
Haematology
Histology
Viability
Fluorinated nucleoside analogues
Apoptosis
Online Access:https://doi.org/10.1007/s12672-023-00829-6

Internet

https://doi.org/10.1007/s12672-023-00829-6

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