PREDICTION OF ANTI-DIABETIC ALOGLIPTIN STABILITY BY ISOTHERMAL STUDIES

PREDICTION OF ANTI-DIABETIC ALOGLIPTIN STABILITY BY ISOTHERMAL STUDIES

Alogliptin (ALG) benzoate is an oral hypoglycemic drug that works as a DPP-4 inhibitor to prevent incretin degradation. Forced stability studies use high temperatures to decompose drugs and estimate their behavior at low temperatures. We aimed to evaluate the thermal stability of ALG using two techn...

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Bibliographic Details
Main Authors: Charise Dallazem Bertol, Gabriel Felimberti, Karini da Rosa, Eliamar Ceresoli Rizzon, Rafael Nicolay Pereira, Luiz Carlos Kreutz, Pedro Eduardo Froelich
Format: Article
Language:English
Published: Sociedade Brasileira de Química 2023-10-01
Series:Química Nova
Subjects:
alogliptin
thermal analysis
LC-PDA
TGA
cytotoxicity
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422023000800765&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422023000800765&lng=en&tlng=en

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