PREDICTION OF ANTI-DIABETIC ALOGLIPTIN STABILITY BY ISOTHERMAL STUDIES

PREDICTION OF ANTI-DIABETIC ALOGLIPTIN STABILITY BY ISOTHERMAL STUDIES

Alogliptin (ALG) benzoate is an oral hypoglycemic drug that works as a DPP-4 inhibitor to prevent incretin degradation. Forced stability studies use high temperatures to decompose drugs and estimate their behavior at low temperatures. We aimed to evaluate the thermal stability of ALG using two techn...

Full description

Bibliographic Details
Main Authors:	Charise Dallazem Bertol, Gabriel Felimberti, Karini da Rosa, Eliamar Ceresoli Rizzon, Rafael Nicolay Pereira, Luiz Carlos Kreutz, Pedro Eduardo Froelich
Format:	Article
Language:	English
Published:	Sociedade Brasileira de Química 2023-10-01
Series:	Química Nova
Subjects:	alogliptin thermal analysis LC-PDA TGA cytotoxicity
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422023000800765&lng=en&tlng=en

Similar Items

CARDIOVASCULAR SAFETY OF GLIPTINS. FOCUS ON ALOGLIPTIN
by: N. A. Petunina, et al.
Published: (2017-12-01)

Formulation and Optimization of Alogliptin-Loaded Polymeric Nanoparticles: In Vitro to In Vivo Assessment
by: Dibyalochan Mohanty, et al.
Published: (2022-07-01)

Possibilities of application a fixed combination of alogliptin and pioglitazone for type 2 diabetes mellitus treatment
by: M. V. Shestakova, et al.
Published: (2021-07-01)

Alogliptin after acute coronary syndrome in patients with type 2 diabetes: a renal function stratified analysis of the EXAMINE trial
by: João Pedro Ferreira, et al.
Published: (2020-06-01)

Salting-out induced liquid–liquid microextraction for alogliptin benzoate determination in human plasma by HPLC/UV
by: Sherin F. Hammad, et al.
Published: (2021-01-01)

Synthesis of a novel analogue of DPP-4 inhibitor Alogliptin: Introduction of a spirocyclic moiety on the piperidine ring
by: Arumugam Kodimuthali, et al.
Published: (2010-07-01)

Alogliptin – the new member of DPP-4 inhibitors class
by: Nina Aleksandrovna Petunina, et al.
Published: (2014-12-01)

Comparison of Efficacy of Glimepiride, Alogliptin, and Alogliptin-Pioglitazone as the Initial Periods of Therapy in Patients with Poorly Controlled Type 2 Diabetes Mellitus: An Open-Label, Multicenter, Randomized, Controlled Study
by: Hae Jin Kim, et al.
Published: (2022-09-01)

Utility of picric acid and 2,4 dinitrophenol as chromogenic reagents for visible spectrophotometric quantification of alogliptin
by: A.V.V.N.K. Sunil Kumar, et al.
Published: (2017-06-01)

A developed HPLC method for the determination of Alogliptin Benzoate and its potential impurities in bulk drug and tablets
by: Kun Zhang, et al.
Published: (2015-04-01)

Alogliptin: efficiency, safety, new possibilities
by: L. Yu. Morgunov
Published: (2020-05-01)

Dipeptidyl-Peptidase-IV Inhibitors, Imigliptin and Alogliptin, Improve Beta-Cell Function in Type 2 Diabetes
by: Xu Liu, et al.
Published: (2021-09-01)

Enantioselective Box Behenken Optimized HPLC-DAD Method for the Simultaneous Estimation of Alogliptin Enantiomorphs in Pharmaceutical For mulations and their Pharmacokinetic Study in Rat Plasma
by: Ravi Kant, et al.
Published: (2019-02-01)

Investigation of Alogliptin-Loaded In Situ Gel Implants by 2<sup>3</sup> Factorial Design with Glycemic Assessment in Rats
by: Tarek M. Ibrahim, et al.
Published: (2022-09-01)

Reliable choice in therapy of type 2 diabetes mellitus: focus on alogliptin
by: N. A. Petunina, et al.
Published: (2019-01-01)

MODERN POSSIBILITIES OF THERAPY OF TYPE 2 DIABETES MELLITUS PATIENTS. EFFECTIVENESS AND CARDIOSAFETY OF ALOGLIPTIN FROM THE POINT OF VIEW OF EVIDENCE-BASED MEDICINE
by: A. S. Ametov, et al.
Published: (2017-07-01)

Alogliptin ameliorates postprandial lipemia and postprandial endothelial dysfunction in non- diabetic subjects: a preliminary report
by: Noda Yoko, et al.
Published: (2013-01-01)

Cardiovascular safety in the treatment of diabetes mellitus type 2: focus on alogliptin
by: A. L. Terekhova, et al.
Published: (2016-12-01)

SYSTEMATIC LITERATURE REVIEW ON CLINICAL EFFICACY AND SAFETY OF ALOGLIPTIN IN COMPARISON WITH VILDAGLIPTIN, LINAGLIPTIN, SAXAGLIPTIN AND SITAGLIPTIN IN ADULT PATIENTS WITH TYPE 2 DIABETES MELLITUS
by: Georgii Rubenovich Khachatryan, et al.
Published: (2015-09-01)

Long-term results of transferring the patient from therapy with glucagon-like peptide-1 receptor agonists in combination with metformin to a dipeptidyl peptidase-4 inhibitor in combination with pioglitazone and inhibitor of type 2 sodium-glucose cotransporter in type 2 diabetes
by: V. V. Salukhov, et al.
Published: (2024-03-01)

Influence of the Type of Soft Segment on the Selected Properties of Polyurethane Materials for Biomedical Applications
by: Andrzej Puszka, et al.
Published: (2024-02-01)

Earth-friendly micellar UPLC technique for determination of four hypoglycemic drugs in different pharmaceutical dosage forms and spiked human plasma
by: Manal S. Elmasry, et al.
Published: (2023-07-01)

Propriedades micromeríticas e análise físico-química de matérias-primas de alopurinol
by: Vanessa Vidaletti Lago, et al.
Published: (2012-07-01)

Propriedades micromeríticas e análise físico-química de matérias-primas de alopurinol
by: Vanessa Vidaletti Lago, et al.
Published: (2012-08-01)

A Comparative and Comprehensive Characterization of Polyphenols of Selected Fruits from the Rosaceae Family
by: Ahsan Hameed, et al.
Published: (2022-03-01)

Synthesis and Evaluation of a Molecularly Imprinted Polymer for Selective Solid-Phase Extraction of Irinotecan from Human Serum Samples
by: Isabelle Lefebvre-Tournier, et al.
Published: (2012-02-01)

Comparative effect of dipeptidyl-peptidase 4 inhibitors on laboratory parameters in patients with diabetes mellitus
by: Yayoi Nishida, et al.
Published: (2020-04-01)

Transcathater percutaneous device closure of a large PDA closed in a 3 kg infant
by: N.O. Bansal, et al.
Published: (2014-11-01)

Effect of Apple Juice Enrichment with Selected Plant Materials: Focus on Bioactive Compounds and Antioxidant Activity
by: Katarzyna Angelika Gil, et al.
Published: (2022-12-01)

HPLC–PDA and LC–MS/MS Analysis for the Simultaneous Quantification of the 14 Marker Components in Sojadodamgangki-Tang
by: Chang-Seob Seo, et al.
Published: (2020-04-01)

Medikal Tedaviye Yanıtsız Duktus Arteriosuslu Preterm İnfantların Tedavisinde Güvenli Bir Yöntem: Yatakbaşı Cerrahi ligasyon
by: Davut Bozkaya, et al.
Published: (2019-06-01)

A Comparative Investigation on Phenolic Composition, Characterization and Antioxidant Potentials of Five Different Australian Grown Pear Varieties
by: Zening Wang, et al.
Published: (2021-01-01)

Fatty Acid Analysis, Chemical Constituents, Biological Activity and Pesticide Residues Screening in Jordanian Propolis
by: Rajashri R. Naik, et al.
Published: (2021-08-01)

Phenolic and carotenoid profile of new goji cultivars and their anti-hyperglycemic, anti-aging and antioxidant properties
by: Aneta Wojdyło, et al.
Published: (2018-09-01)

Comparison of bioactive potential of cranberry fruit and fruit-based products versus leaves
by: Jan Oszmiański, et al.
Published: (2016-04-01)

THE PHENOLIC COMPOSITION OF THE HEPATOPROTECTIVE AND ANTIOXIDANT FRACTIONS OF Albizia lebbeck L.
by: Nadia M. Sokkar, et al.

Identification and Structural Characterization of Degradation Products of Linagliptin by Mass Spectrometry Techniques
by: Aleksandra Liana, et al.
Published: (2024-02-01)

Tiroid fonksiyonunun prematüre bebeklerde patent duktus arteriozus üzerine etkisi
by: Cüneyt Tayman, et al.
Published: (2019-03-01)

Model-Fitting Approach to Kinetic Analysis of Non-Isothermal Oxidation of Molybdenite
by: Reza Ebrahimi Kahrizsangi, et al.
Published: (2007-06-01)

LC-ESI-QTOF-MS/MS Characterization of Seaweed Phenolics and Their Antioxidant Potential
by: Biming Zhong, et al.
Published: (2020-06-01)