Arsenic Induces p62 Expression to Form a Positive Feedback Loop with Nrf2 in Human Epidermal Keratinocytes: Implications for Preventing Arsenic-Induced Skin Cancer

Arsenic Induces p62 Expression to Form a Positive Feedback Loop with Nrf2 in Human Epidermal Keratinocytes: Implications for Preventing Arsenic-Induced Skin Cancer

Exposure to inorganic arsenic in contaminated drinking water poses an environmental public health threat for hundreds of millions of people in the US and around the world. Arsenic is a known carcinogen for skin cancer. However, the mechanism by which arsenic induces skin cancer remains poorly unders...

Full description

Bibliographic Details
Main Authors: Palak Shah, Elaine Trinh, Lei Qiang, Lishi Xie, Wen-Yang Hu, Gail S. Prins, Jingbo Pi, Yu-Ying He
Format: Article
Language:English
Published: MDPI AG 2017-01-01
Series:Molecules
Subjects:
arsenic
p62
Nrf2
keratinocytes
apoptosis
proliferation
Online Access:http://www.mdpi.com/1420-3049/22/2/194

Internet

http://www.mdpi.com/1420-3049/22/2/194

Similar Items