A novel immunodeficient NOD.SCID-rd1 mouse model of retinitis pigmentosa to investigate potential therapeutics and pathogenesis of retinal degeneration

A novel immunodeficient NOD.SCID-rd1 mouse model of retinitis pigmentosa to investigate potential therapeutics and pathogenesis of retinal degeneration

Retinitis pigmentosa (RP) is a common retinal degeneration disease caused by mutation in any gene of the photo transduction cascade and results in photoreceptor dystrophy. Over decades, several animal models have been used to address the need for the elucidation of effective therapeutics and factors...

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Bibliographic Details
Main Authors: Alaknanda Mishra, Barun Das, Madhu Nath, Srikanth Iyer, Ashwani Kesarwani, Jashdeep Bhattacharjee, Shailendra Arindkar, Preeti Sahay, Kshama Jain, Parul Sahu, Prakriti Sinha, Thirumurthy Velpandian, Perumal Nagarajan, Pramod Upadhyay
Format: Article
Language:English
Published: The Company of Biologists 2017-04-01
Series:Biology Open
Subjects:
Retinitis pigmentosa
NOD.SCID-rd1 mouse model
Immunocompromised mouse
Cell based therapeutics
Online Access:http://bio.biologists.org/content/6/4/449

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http://bio.biologists.org/content/6/4/449

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