Genome-Scale Metabolic Model of the Human Pathogen <i>Candida albicans</i>: A Promising Platform for Drug Target Prediction

Genome-Scale Metabolic Model of the Human Pathogen <i>Candida albicans</i>: A Promising Platform for Drug Target Prediction

<i>Candida albicans</i> is one of the most impactful fungal pathogens and the most common cause of invasive candidiasis, which is associated with very high mortality rates. With the rise in the frequency of multidrug-resistant clinical isolates, the identification of new drug targets and...

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Bibliographic Details
Main Authors: Romeu Viana, Oscar Dias, Davide Lagoa, Mónica Galocha, Isabel Rocha, Miguel Cacho Teixeira
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Journal of Fungi
Subjects:
<i>Candida albicans</i>
global stoichiometric model
drug targets
metabolic reconstruction
gene essentiality
Online Access:https://www.mdpi.com/2309-608X/6/3/171

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https://www.mdpi.com/2309-608X/6/3/171

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