Effect of urea and tmao on lipid bilayers

We study the effect of the osmolytes, Urea and trimethylamine-N-oxide (TMAO) on POPE (1-palmitoyl-2-oleoyl-sn-glycero-3- phosphoethanolamine) lipid membranes using SAXS/WAXS and DSC. Their antagonist effect is observed with TMAO stabilizing and Urea destabilizing the lipid bilayer, as seen by others...

Full description

Bibliographic Details
Main Authors: Valerio J., Bernstorff S., Funari S.S.
Format: Article
Language:English
Published: Sciendo 2017-11-01
Series:European Pharmaceutical Journal
Subjects:
Online Access:https://doi.org/10.1515/afpuc-2017-0003