Comparison of the efficacy and tolerability of elobixibat plus sodium picosulfate with magnesium citrate and split-dose 2-L polyethylene glycol with ascorbic acid for bowel preparation before outpatient colonoscopy: a study protocol for the multicentre, randomised, controlled E-PLUS trial

Comparison of the efficacy and tolerability of elobixibat plus sodium picosulfate with magnesium citrate and split-dose 2-L polyethylene glycol with ascorbic acid for bowel preparation before outpatient colonoscopy: a study protocol for the multicentre, randomised, controlled E-PLUS trial

Abstract Background Sodium picosulfate (SP)/magnesium citrate (MC) and polyethylene glycol (PEG) plus ascorbic acid are recommended by Western guidelines as laxative solutions for bowel preparation. Clinically, SP/MC has a slower post-dose defaecation response than PEG and is perceived as less clean...

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Main Authors: Kinichi Hotta, Yosuke Otake, Daisuke Yamaguchi, Yuichi Shimodate, Norihiro Hanabata, Hiroaki Ikematsu, Yohei Yabuuchi, Yasushi Sano, Ryo Shimoda, Shinya Sugimoto, Mari Oba, Hiroyuki Takamaru, Kouichiro Kimura, Yoshihiro Kishida, Kazunori Takada, Sayo Ito, Kenichiro Imai, Kazuya Hosotani, Tatsuro Murano, Masayoshi Yamada, Kensuke Shinmura, Rio Takezawa, Michito Tomonaga, Yutaka Saito
Format: Article
Language:English
Published: BMC 2024-02-01
Series:BMC Gastroenterology
Subjects:
Boston bowel preparation scale
Bowel preparation
Colonoscopy
Elobixibat
Polyethylene glycol
Sodium picosulfate magnesium citrate
Online Access:https://doi.org/10.1186/s12876-024-03146-6

Internet

https://doi.org/10.1186/s12876-024-03146-6

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