SIRPα blockade improves the antitumor immunity of radiotherapy in colorectal cancer

Abstract High-dose hypofractionated radiotherapy (HRT) is an important anticancer treatment modality that activates antitumor host immune responses. However, HRT for oligometastases of colorectal cancer (CRC) has shown frustrating results in the clinic. As part of immune evasion, myeloid cells expre...

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Bibliographic Details
Main Authors: Kai Ji, Yuhan Zhang, Shengpeng Jiang, Lin Sun, Baozhong Zhang, Dongzhi Hu, Jun Wang, Lujun Zhao, Ping Wang, Zhen Tao
Format: Article
Language:English
Published: Nature Publishing Group 2023-06-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-023-01472-4