The population context is a driver of the heterogeneous response of epithelial cells to interferons

The population context is a driver of the heterogeneous response of epithelial cells to interferons

Abstract Isogenic cells respond in a heterogeneous manner to interferon. Using a micropatterning approach combined with high-content imaging and spatial analyses, we characterized how the population context (position of a cell with respect to neighboring cells) of epithelial cells affects their resp...

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Bibliographic Details
Main Authors: Camila Metz-Zumaran, Zina M Uckeley, Patricio Doldan, Francesco Muraca, Yagmur Keser, Pascal Lukas, Benno Kuropka, Leonie Küchenhoff, Soheil Rastgou Talemi, Thomas Höfer, Christian Freund, Elisabetta Ada Cavalcanti-Adam, Frederik Graw, Megan Stanifer, Steeve Boulant
Format: Article
Language:English
Published: Springer Nature 2024-01-01
Series:Molecular Systems Biology
Subjects:
Interferons
Heterogeneity
Population Context
Epithelium
Polarity
Online Access:https://doi.org/10.1038/s44320-024-00011-2

Internet

https://doi.org/10.1038/s44320-024-00011-2

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