Clinically Relevant Oxygraphic Assay to Assess Mitochondrial Energy Metabolism in Acute Myeloid Leukemia Patients

Clinically Relevant Oxygraphic Assay to Assess Mitochondrial Energy Metabolism in Acute Myeloid Leukemia Patients

Resistant acute myeloid leukemia (AML) exhibits mitochondrial energy metabolism changes compared to newly diagnosed AML. This phenotype is often observed by evaluating the mitochondrial oxygen consumption of blasts, but most of the oximetry protocols were established from leukemia cell lines without...

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Bibliographic Details
Main Authors: Quentin Fovez, William Laine, Laure Goursaud, Celine Berthon, Nicolas Germain, Claire Degand, Jean-Emmanuel Sarry, Bruno Quesnel, Philippe Marchetti, Jerome Kluza
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Cancers
Subjects:
energy metabolism
leukemia
resistance
functional biomarker
uncoupling respiration
OCR
Online Access:https://www.mdpi.com/2072-6694/13/24/6353

Internet

https://www.mdpi.com/2072-6694/13/24/6353

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