Muscle Specific miRNAs are induced by testosterone and independently upregulated by age.

Muscle Specific miRNAs are induced by testosterone and independently upregulated by age.

Age dependent decline in skeletal muscle function leads to impaired metabolic flexibility in elderly individuals. Physical activity and testosterone treatment have proven efficient strategies for delaying this condition. However, a common molecular pathway has not been identified. Muscle specific mi...

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Bibliographic Details
Main Authors: Søren eNielsen, Thine eHvid, Meghan eKelly, Birgitte eLindegaard, Christine eDethlefsen, Kamilla eWinding, Neha eMathur, Camilla eScheele, Bente Klarlund Pedersen, Matthew J. Laye
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-01-01
Series:Frontiers in Physiology
Subjects:
Aging
Exercise
gender
miRNA
skeletal muscle
myomiRs
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2013.00394/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphys.2013.00394/full

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