Tumor-infiltrating CCR2+ inflammatory monocytes counteract specific immunotherapy

Tumor-infiltrating CCR2+ inflammatory monocytes counteract specific immunotherapy

Tumor development and progression is shaped by the tumor microenvironment (TME), a heterogeneous assembly of infiltrating and resident host cells, their secreted mediators and intercellular matrix. In this context, tumors are infiltrated by various immune cells with either pro-tumoral or anti-tumora...

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Bibliographic Details
Main Authors: Joschka Bartneck, Ann-Kathrin Hartmann, Lara Stein, Danielle Arnold-Schild, Matthias Klein, Michael Stassen, Federico Marini, Jonas Pielenhofer, Sophie Luise Meiser, Peter Langguth, Matthias Mack, Sabine Muth, Hans-Christian Probst, Hansjörg Schild, Markus Philipp Radsak
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Immunology
Subjects:
cancer immunotherapy
transcutaneous immunization
tumor micro environment (TME)
immune evasion
CCR2 monocytes +
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1267866/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1267866/full

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