AGNEP: An Agglomerative Nesting Clustering Algorithm for Phenotypic Dimension Reduction in Joint Analysis of Multiple Phenotypes

AGNEP: An Agglomerative Nesting Clustering Algorithm for Phenotypic Dimension Reduction in Joint Analysis of Multiple Phenotypes

Genome-wide association study (GWAS) has identified thousands of genetic variants associated with complex traits and diseases. Compared with analyzing a single phenotype at a time, the joint analysis of multiple phenotypes can improve statistical power by taking into account the information from phe...

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Bibliographic Details
Main Authors: Fengrong Liu, Ziyang Zhou, Mingzhi Cai, Yangjun Wen, Jin Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Genetics
Subjects:
genome-wide association study
statistical power
clustering algorithms
principal component analysis
genetic structure
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.648831/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2021.648831/full

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