pH-Responsive Lipid Nanocapsules: A Promising Strategy for Improved Resistant Melanoma Cell Internalization

Despite significant advances in melanoma therapy, low response rates and multidrug resistance (MDR) have been described, reducing the anticancer efficacy of the administered molecules. Among the causes to explain these resistances, the decreased intratumoral pH is known to potentiate MDR and to redu...

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Bibliographic Details
Main Authors: Vincent Pautu, Elise Lepeltier, Adélie Mellinger, Jérémie Riou, Antoine Debuigne, Christine Jérôme, Nicolas Clere, Catherine Passirani
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/13/9/2028