PIRT the TRP Channel Regulating Protein Binds Calmodulin and Cholesterol-Like Ligands

Transient receptor potential (TRP) ion channels are polymodal receptors that have been implicated in a variety of pathophysiologies, including pain, obesity, and cancer. The capsaicin and heat sensor TRPV1, and the menthol and cold sensor TRPM8, have been shown to be modulated by the membrane protei...

Full description

Bibliographic Details
Main Authors: Nicholas J. Sisco, Dustin D. Luu, Minjoo Kim, Wade D. Van Horn
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/10/3/478