Development of Antibody–Drug Conjugates Using DDS and Molecular Imaging

Development of Antibody–Drug Conjugates Using DDS and Molecular Imaging

Antibody-drug conjugate (ADC), as a next generation of antibody therapeutics, is a combination of an antibody and a drug connected via a specialized linker. ADC has four action steps: systemic circulation, the enhanced permeability and retention (EPR) effect, penetration within the tumor tissue, and...

Full description

Bibliographic Details
Main Authors: Masahiro Yasunaga, Shino Manabe, Atsushi Tsuji, Masaru Furuta, Koretsugu Ogata, Yoshikatsu Koga, Tsuneo Saga, Yasuhiro Matsumura
Format: Article
Language:English
Published: MDPI AG 2017-09-01
Series:Bioengineering
Subjects:
ADC (antibody-drug conjugate)
DDS (drug delivery system)
molecular imaging
antibody delivery
controlled release
PET (positron emission tomography)
MSI (mass spectrometry imaging)
Online Access:https://www.mdpi.com/2306-5354/4/3/78

Internet

https://www.mdpi.com/2306-5354/4/3/78

Similar Items