Vitamin B12-Induced Autophagy Alleviates High Glucose-Mediated Apoptosis of Islet β Cells

Vitamin B12-Induced Autophagy Alleviates High Glucose-Mediated Apoptosis of Islet β Cells

High glucose levels can lead to the apoptosis of islet β cells, while autophagy can provide cytoprotection and promote autophagic cell death. Vitamin B12, a water-soluble B vitamin, has been shown to regulate insulin secretion and increase insulin sensitivity. However, the precise mechanism of actio...

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Bibliographic Details
Main Authors: Yu Zhang, Ling Chu, Xi’an Zhou, Tingxia Xu, Qingwu Shen, Tao Li, Yanyang Wu
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:International Journal of Molecular Sciences
Subjects:
apoptosis
autophagy
diabetes
high glucose
vitamin B12
Online Access:https://www.mdpi.com/1422-0067/24/20/15217

Internet

https://www.mdpi.com/1422-0067/24/20/15217

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