Good Cop, Bad Cop: Defining the Roles of Δ40p53 in Cancer and Aging

The tumour suppressor p53 is essential for maintaining DNA integrity, and plays a major role in cellular senescence and aging. Understanding the mechanisms that contribute to p53 dysfunction can uncover novel possibilities for improving cancer therapies and diagnosis, as well as cognitive decline as...

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Bibliographic Details
Main Authors: Luiza Steffens Reinhardt, Xiajie Zhang, Anna Wawruszak, Kira Groen, Geoffry N. De Iuliis, Kelly A. Avery-Kiejda
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/12/6/1659