Lin11-Isl1-Mec3 Domain Proteins as Mechanotransducers in Endothelial and Vascular Smooth Muscle Cells

Arterial hypertension is the leading risk factor for cardiovascular morbidity and mortality worldwide. However, little is known about the cellular mechanisms underlying it. In small arteries and arterioles, a chronic increase in blood pressure raises wall tension and hence stretches, namely, the med...

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Bibliographic Details
Main Authors: Alexandra Sporkova, Subhajit Ghosh, Jaafar Al-Hasani, Markus Hecker
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.769321/full