Apolipoprotein L1 is increased in frontotemporal lobar degeneration post-mortem brain but not in ante-mortem cerebrospinal fluid

Apolipoprotein L1 is increased in frontotemporal lobar degeneration post-mortem brain but not in ante-mortem cerebrospinal fluid

Aims: Frontotemporal Dementia (FTD) is caused by frontal-temporal lobar degeneration (FTLD), characterized mainly by brain protein aggregates of tau (FTLD-Tau) or TDP-43 (FTLD-TDP). The clinicopathological heterogeneity makes ante-mortem diagnosis of these pathological subtypes challenging. Our prot...

Full description

Bibliographic Details
Main Authors: Yanaika S. Hok-A-Hin, Anke A. Dijkstra, Alberto Rábano, Jeroen J. Hoozemans, Lucía Castillo, Harro Seelaar, John C. van Swieten, Yolande A.L. Pijnenburg, Charlotte E. Teunissen, Marta del Campo
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:Neurobiology of Disease
Subjects:
APOL1
CSF
Brain tissue
FTD
FTLD-tau
FTLD-TDP
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996122002054

Internet

http://www.sciencedirect.com/science/article/pii/S0969996122002054

Similar Items