Down-Regulation of PDCD4 Promotes Proliferation, Angiogenesis and Tumorigenesis in Glioma Cells

Down-Regulation of PDCD4 Promotes Proliferation, Angiogenesis and Tumorigenesis in Glioma Cells

The programmed cell death 4 (PDCD4) tumor-suppressor gene regulates cell apoptosis, protein translation, signal transduction, and induction of mediators of inflammation. However, the mechanism by which PDCD4 is down-regulated and regulates tumor growth remains elusive. In this study, we showed that...

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Bibliographic Details
Main Authors: Guo Pin, Li Huanting, Zhu Chengzhan, Kong Xinjuan, Feng Yugong, Liu Wei, Li Shifang, Li Zhaojian, Han Kun, Yao Weicheng, Lin Yingying, Qiu Yongming, Yu Yanan
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
glioma
PDCD4
AKT
STAT3
angiogenesis
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2020.593685/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2020.593685/full

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