Down-Regulation of PDCD4 Promotes Proliferation, Angiogenesis and Tumorigenesis in Glioma Cells

Down-Regulation of PDCD4 Promotes Proliferation, Angiogenesis and Tumorigenesis in Glioma Cells

The programmed cell death 4 (PDCD4) tumor-suppressor gene regulates cell apoptosis, protein translation, signal transduction, and induction of mediators of inflammation. However, the mechanism by which PDCD4 is down-regulated and regulates tumor growth remains elusive. In this study, we showed that...

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Bibliographic Details
Main Authors:	Guo Pin, Li Huanting, Zhu Chengzhan, Kong Xinjuan, Feng Yugong, Liu Wei, Li Shifang, Li Zhaojian, Han Kun, Yao Weicheng, Lin Yingying, Qiu Yongming, Yu Yanan
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2020-11-01
Series:	Frontiers in Cell and Developmental Biology
Subjects:	glioma PDCD4 AKT STAT3 angiogenesis
Online Access:	https://www.frontiersin.org/articles/10.3389/fcell.2020.593685/full

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