The Influence of Cannabidiol on the Pharmacokinetics of Methylphenidate in Healthy Subjects

The Influence of Cannabidiol on the Pharmacokinetics of Methylphenidate in Healthy Subjects

Introduction: Cannabidiol (CBD) is a widely utilized nonpsychoactive cannabinoid available as an over-the-counter supplement, a component of medical cannabis, and a prescriptive treatment of childhood epilepsies. In vitro studies suggest CBD may inhibit a number of drug-metabolizing enzymes, includi...

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Bibliographic Details
Main Authors: John S. Markowitz, Ludmila De Faria, Qingchen Zhang, Philip W. Melchert, Reginald F. Frye, Brandon O. Klee, Yuli Qian
Format: Article
Language:English
Published: Karger Publishers 2022-11-01
Series:Medical Cannabis and Cannabinoids
Subjects:
cannabidiol
drug interaction
carboxylesterase
methylphenidate
carboxylesterase 1
cannabis
Online Access:https://www.karger.com/Article/FullText/527189

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https://www.karger.com/Article/FullText/527189

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