Dysfunction of the hypothalamic-pituitary adrenal axis and its influence on aging: the role of the hypothalamus

Abstract As part of the hypothalamic-pituitary adrenal (HPA) axis, the hypothalamus exerts pivotal influence on metabolic and endocrine homeostasis. With age, these processes are subject to considerable change, resulting in increased prevalence of physical disability and cardiac disorders. Yet, rese...

Full description

Bibliographic Details
Main Authors: Melanie Spindler, Marco Palombo, Hui Zhang, Christiane M. Thiel
Format: Article
Language:English
Published: Nature Portfolio 2023-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-33922-5