15727 KATP channel prodrugs as therapeutics for chronic pain and substance abuse disorders

ABSTRACT IMPACT: Pharmacological activation of KATP channels may provide analgesia and attenuate opioid tolerance and withdrawal OBJECTIVES/GOALS: Our long term goal is to develop therapeutics for the treatment of the overuse of opioids. The objective of this application is to test novel KATP channe...

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Bibliographic Details
Main Authors: Alexis Doucette, Kayla Johnson, Peter I. Dosa, Amanda H Klein
Format: Article
Language:English
Published: Cambridge University Press 2021-03-01
Series:Journal of Clinical and Translational Science
Online Access:https://www.cambridge.org/core/product/identifier/S2059866121004222/type/journal_article