OTOGL, a gelforming mucin protein, is nonessential for male germ cell development and spermatogenesis in mice

OTOGL, a gelforming mucin protein, is nonessential for male germ cell development and spermatogenesis in mice

Abstract Otogelin-like protein (encoded by Otogl) was highly structural similar to the gelforming mucin proteins. Although human OTOG mutations have been linked to deafness, the biological function of OTOGL in male germ cell development remains enigmatic. In screening 336 patients with non-obstructi...

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Bibliographic Details
Main Authors: Zhiming Li, Yan Zhang, Xinzong Zhang, Congcong Cao, Xiaomin Luo, Yaoting Gui, Yunge Tang, Shuiqiao Yuan
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Reproductive Biology and Endocrinology
Subjects:
OTOGL
Spermatogenesis
Fertility
Knockout mouse model
CRISPR/Cas9
Online Access:https://doi.org/10.1186/s12958-021-00779-0

Internet

https://doi.org/10.1186/s12958-021-00779-0

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