Longitudinal evaluation of cerebral and spinal cord damage in Amyotrophic Lateral Sclerosis

Longitudinal evaluation of cerebral and spinal cord damage in Amyotrophic Lateral Sclerosis

Objective: To evaluate MRI-based parameters as biomarkers of Amyotrophic Lateral Sclerosis (ALS) progression. Methods: Twenty-seven patients and 27 controls performed two clinical and MRI acquisitions 8 months apart. ALSFRS-R scale was used to quantify disease severity at both time points. Multimoda...

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Bibliographic Details
Main Authors: Milena de Albuquerque, Lucas Melo T Branco, Thiago Junqueira R. Rezende, Helen Maia Tavares de Andrade, Anamarli Nucci, Marcondes Cavalcante França Jr
Format: Article
Language:English
Published: Elsevier 2017-01-01
Series:NeuroImage: Clinical
Subjects:
MRI
Amyotrophic Lateral Sclerosis
Cortical thickness
TBSS
Spinal cord
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158217300256

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http://www.sciencedirect.com/science/article/pii/S2213158217300256

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