Cytotoxic Mechanism of Momilactones A and B against Acute Promyelocytic Leukemia and Multiple Myeloma Cell Lines

Cytotoxic Mechanism of Momilactones A and B against Acute Promyelocytic Leukemia and Multiple Myeloma Cell Lines

This is the first study clarifying the cytotoxic mechanism of momilactones A (MA) and B (MB) on acute promyelocytic leukemia (APL) HL-60 and multiple myeloma (MM) U266 cell lines. Via the MTT test, MB and the mixture MAB (1:1, <i>w</i>/<i>w</i>) exhibit a potent cytotoxicity...

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Bibliographic Details
Main Authors: La Hoang Anh, Vu Quang Lam, Akiyoshi Takami, Tran Dang Khanh, Nguyen Van Quan, Tran Dang Xuan
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Cancers
Subjects:
momilactones
leukemia
multiple myeloma
cytotoxic mechanism
apoptosis
cell cycle
Online Access:https://www.mdpi.com/2072-6694/14/19/4848

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https://www.mdpi.com/2072-6694/14/19/4848

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