Development of Dicationic Bisguanidine-Arylfuran Derivatives as Potent Agents against Gram-Negative Bacteria

Development of Dicationic Bisguanidine-Arylfuran Derivatives as Potent Agents against Gram-Negative Bacteria

Antibiotic resistance among bacteria is a growing global challenge. A major reason for this is the limited progress in developing new classes of antibiotics active against Gram-negative bacteria. Here, we investigate the antibacterial activity of a dicationic bisguanidine-arylfuran, originally devel...

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Bibliographic Details
Main Authors: Catarina Bourgard, Diego Rodríguez-Hernández, Anastasia Rudenko, Carolin Rutgersson, Martin Palm, D. G. Joakim Larsson, Anne Farewell, Morten Grøtli, Per Sunnerhagen
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Antibiotics
Subjects:
antibiotic resistance
antimicrobial activity
<i>Escherichia coli</i>
ESKAPE bacteria
dicationic compounds
sensitivity profiling
Online Access:https://www.mdpi.com/2079-6382/11/8/1115

Internet

https://www.mdpi.com/2079-6382/11/8/1115

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