The immune cell landscape of glioblastoma patients highlights a myeloid-enriched and immune suppressed microenvironment compared to metastatic brain tumors

The immune cell landscape of glioblastoma patients highlights a myeloid-enriched and immune suppressed microenvironment compared to metastatic brain tumors

IntroductionBrain metastases (BrM), which commonly arise in patients with melanoma, breast cancer and lung cancer, are associated with a poor clinical prognosis. In this context, the tumor microenvironment (TME) plays an important role since it either promotes or inhibits tumor progression. Our prev...

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Bibliographic Details
Main Authors: Beatrice Musca, Maria Giovanna Russo, Ada Tushe, Sara Magri, Greta Battaggia, Laura Pinton, Camilla Bonaudo, Alessandro Della Puppa, Susanna Mandruzzato
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Immunology
Subjects:
brain metastases
glioblastoma
tumor microenvironment
tumor-associated macrophages
myeloid cells
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1236824/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1236824/full

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