Hydroxychloroquine and azithromycin alter the contractility of living porcine heart slices

Hydroxychloroquine and azithromycin alter the contractility of living porcine heart slices

The cardiotoxicity risk of hydroxychloroquine (HCQ) and azithromycin (AZM) has been the subject of intensive research triggered by safety concerns in COVID-19 patients. HCQ and AZM have been associated with QT interval prolongation and drug-induced arrhythmias, however other cardiotoxicity mechanism...

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Những tác giả chính: Qin Wu, Abigail J. Ross, Tugce Ipek, Georgina H. Thompson, Robert D. Johnson, Changhao Wu, Patrizia Camelliti
Định dạng: Bài viết
Ngôn ngữ:English
Được phát hành: Frontiers Media S.A. 2023-05-01
Loạt:Frontiers in Pharmacology
Những chủ đề:
myocardial slices
organotypic ex-vivo models
COVID-19
cardiotoxicity
safety pharmacology
calcium channels
Truy cập trực tuyến:https://www.frontiersin.org/articles/10.3389/fphar.2023.1127388/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2023.1127388/full

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