Hydroxychloroquine and azithromycin alter the contractility of living porcine heart slices

The cardiotoxicity risk of hydroxychloroquine (HCQ) and azithromycin (AZM) has been the subject of intensive research triggered by safety concerns in COVID-19 patients. HCQ and AZM have been associated with QT interval prolongation and drug-induced arrhythmias, however other cardiotoxicity mechanism...

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Hlavní autoři: Qin Wu, Abigail J. Ross, Tugce Ipek, Georgina H. Thompson, Robert D. Johnson, Changhao Wu, Patrizia Camelliti
Médium: Článek
Jazyk:English
Vydáno: Frontiers Media S.A. 2023-05-01
Edice:Frontiers in Pharmacology
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On-line přístup:https://www.frontiersin.org/articles/10.3389/fphar.2023.1127388/full