The role of polymorphisms of thiopurine methyltransferase in therapy with Azathioprine: preliminary study

Azathioprine is an immunosuppressant drug belonging to the class of thiopurines widely used in clinical therapy. Its immunosuppressive action is linked to the substantial action mechanism in the inhibition of the synthesis of nitrogenous bases purine carried out in T-lymphocyte. The level of such me...

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Bibliographic Details
Main Authors: Francesca Mortillaro, Carmelo Fabiano, Maria Piccione, Marco Giammanco, Fabio Venturella
Format: Article
Language:English
Published: PAGEPress Publications 2018-11-01
Series:Journal of Biological Research
Subjects:
Online Access:https://www.pagepressjournals.org/index.php/jbr/article/view/7717