A Novel Huntington’s Disease Assessment Platform to Support Future Drug Discovery and Development

A Novel Huntington’s Disease Assessment Platform to Support Future Drug Discovery and Development

Huntington’s disease (HD) is a lethal neurodegenerative disorder without efficient therapeutic options. The inefficient translation from preclinical and clinical research into clinical use is mainly attributed to the lack of (i) understanding of disease initiation, progression, and involved molecula...

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Bibliographic Details
Main Authors: Jingyun Wu, Luisa Möhle, Thomas Brüning, Iván Eiriz, Muhammad Rafehi, Katja Stefan, Sven Marcel Stefan, Jens Pahnke
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:International Journal of Molecular Sciences
Subjects:
Huntington’s disease
neurodegeneration
therapy
drug discovery
drug design
ABC transporters
Online Access:https://www.mdpi.com/1422-0067/23/23/14763

Internet

https://www.mdpi.com/1422-0067/23/23/14763

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